Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | BT_ATM_minus |
| GeneSet | NCI_RAS SIGNALING IN THE CD4+ TCR PATHWAY |
| Enrichment Score (ES) | -0.62977386 |
| Normalized Enrichment Score (NES) | -1.6783111 |
| Nominal p-value | 0.009578544 |
| FDR q-value | 0.2517771 |
| FWER p-Value | 0.895 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | IL2RA | 1420691_at 1420692_at | 108 | 2.955 | 0.1025 | No | ||
| 2 | KRAS | 1426228_at 1426229_s_at 1434000_at 1451979_at | 457 | 1.725 | 0.1494 | No | ||
| 3 | CALM2 | 1422414_a_at 1423807_a_at | 2762 | 0.525 | 0.0633 | No | ||
| 4 | IFNG | 1425947_at | 6045 | 0.227 | -0.0783 | No | ||
| 5 | MAP2K1 | 1416351_at | 6588 | 0.201 | -0.0958 | No | ||
| 6 | IL3 | 1450566_at | 7599 | 0.155 | -0.1363 | No | ||
| 7 | AKAP5 | 1447301_at | 8177 | 0.134 | -0.1577 | No | ||
| 8 | PRKCA | 1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at | 8674 | 0.116 | -0.1762 | No | ||
| 9 | CD40LG | 1422283_at | 9841 | 0.076 | -0.2266 | No | ||
| 10 | PTGS2 | 1417262_at 1417263_at | 10217 | 0.063 | -0.2414 | No | ||
| 11 | FASLG | 1418803_a_at 1449235_at | 10804 | 0.043 | -0.2666 | No | ||
| 12 | NFATC2 | 1425901_at 1425990_a_at 1426031_a_at 1426032_at 1439205_at 1440426_at | 11899 | 0.006 | -0.3163 | No | ||
| 13 | HRAS | 1422407_s_at 1424132_at | 12396 | -0.011 | -0.3386 | No | ||
| 14 | NRAS | 1422688_a_at 1454060_a_at | 12913 | -0.030 | -0.3610 | No | ||
| 15 | FOSL1 | 1417487_at 1417488_at | 13122 | -0.038 | -0.3691 | No | ||
| 16 | BRAF | 1425693_at 1435434_at 1435480_at 1442749_at 1445786_at 1447940_a_at 1447941_x_at 1456505_at 1458641_at | 13208 | -0.041 | -0.3715 | No | ||
| 17 | CSF2 | 1427429_at | 14310 | -0.086 | -0.4187 | No | ||
| 18 | MAP3K8 | 1419208_at | 14885 | -0.112 | -0.4408 | No | ||
| 19 | POU2F1 | 1419716_a_at 1427695_a_at 1427835_at | 15180 | -0.126 | -0.4496 | No | ||
| 20 | IL4 | 1449864_at | 15504 | -0.141 | -0.4592 | No | ||
| 21 | PRKACA | 1447720_x_at 1450519_a_at | 15605 | -0.147 | -0.4585 | No | ||
| 22 | CALM1 | 1417365_a_at 1417366_s_at 1433592_at 1454611_a_at 1455571_x_at | 15802 | -0.158 | -0.4616 | No | ||
| 23 | FOS | 1423100_at | 16233 | -0.185 | -0.4746 | No | ||
| 24 | JUN | 1417409_at 1448694_at | 17249 | -0.260 | -0.5115 | No | ||
| 25 | CALM3 | 1426710_at 1438825_at 1438826_x_at 1450864_at | 17944 | -0.333 | -0.5310 | No | ||
| 26 | MAPK3 | 1427060_at | 19743 | -0.679 | -0.5884 | Yes | ||
| 27 | RAF1 | 1416078_s_at 1425419_a_at | 20370 | -0.914 | -0.5838 | Yes | ||
| 28 | JUNB | 1415899_at | 21378 | -1.811 | -0.5639 | Yes | ||
| 29 | NFATC3 | 1419976_s_at 1452497_a_at | 21380 | -1.817 | -0.4979 | Yes | ||
| 30 | ELK1 | 1421896_at 1421897_at 1446390_at | 21389 | -1.836 | -0.4315 | Yes | ||
| 31 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 21451 | -1.949 | -0.3634 | Yes | ||
| 32 | NFATC1 | 1417621_at 1425761_a_at 1428479_at 1447084_at 1447085_s_at | 21857 | -3.609 | -0.2506 | Yes | ||
| 33 | FKBP1A | 1416036_at 1438795_x_at 1438958_x_at 1448184_at 1456196_x_at | 21931 | -6.986 | 0.0001 | Yes |
